Eddie Murphy
Dr. John Dolittle
Kristen Wilson
Lisa Dolittle
Kyla Pratt
Maya Dolittle
Raven-Symoné
Charisse Dolittle
Steve Zahn
Archie (voice)
Lisa Kudrow
Ava (voice)
James Avery
Eldon
Andy Richter
Eugene Wilson
Lil' Zane
Eric
Denise Dowse
Secretary
Elayn J. Taylor
Eldon's Wife
Kevin Pollak
Riley / Alligator
Victor Raider-Wexler
Judge B. Duff
Jeffrey Jones
Joe Potter
Mark Griffin
Logger / Nature Show Narrator
Ken Hudson Campbell
Animal Control Officer / Dog / Animal Groupie #3 / Forest Animal (voice)
Anne Stedman
Woman
Tommy Bush
Farmer
Adam Vernier
Farm Worker
Chris Marley
Yuppie Man
Shaun Robinson
Newscaster
Googy Gress
Bear Announcer
Lisa Marie Hugueley
Shamu Trainer
Steve Irwin
The Crocodile Hunter
Doug Seus
Klondike Dave Delivery Man
Louise Osbourne
Waitress
Brie Hill Arbaugh
Chihuahua Lady
E.J. Wessel
Guy Throwing Frisbee
Jacob Vargas
Pepito (voice)
Michael Rapaport
Joey the Raccoon (Voice)
Isaac Hayes
Possum (voice)
Andy Dick
Lennie the Weasel (voice)
Joey Lauren Adams
Squirrel (voice)
Maria Arcé
Fish (voice)
Melique Berger
Fish (voice)
David Cross
Dog / Animal Groupie #2 (voice)
David DeLuise
School Fish #2 (voice)
Trevor Denman
Horse Race Announcer (voice)
John DiMaggio
Seeing Eye Dog / Wassup Fish / Mouse (voice)
Georgia Engel
Giraffe (voice)
Mike Epps
Sonny (voice)
Jamie Kennedy
Bandit / Forest Animal / Animal Groupie #1 (voice)
Tom Kenny
Male Tortoise (voice)
Clyde Kusatsu
Bee (voice)
Cedric the Entertainer
Zoo Bear #1 (voice)
David L. Lander
Bird (voice)
Michael McKean
Bird (voice)
Tara Mercurio
Deer (voice)
Mandy Moore
Girl Bear Cub
Frankie Muniz
Boy Bear Cub (voice)
Bob Odenkirk
Animal Groupie #4 / Forest Animal / Dog (voice)
Phil Proctor
Drunk Monkey (voice)
Reni Santoni
Rat #2 (voice)
Richard C. Sarafian
God Beaver (voice)
Hal Sparks
School Fish #1 (voice)
Renée Taylor
Female Tortoise (voice)
John Witherspoon
Zoo Bear #2 (voice)
Keone Young
Bee (voice)
Jodi Essex
Frisbee Thrower in Park (uncredited)
Lawrence Pressman
Governor of California (uncredited)
Norm Macdonald
Lucky (voice)
Crystal the Monkey
Drunk Monkey (uncredited)
Bart the Bear II
Boy Bear Cub
Arnold Schwarzenegger
White Wolf (voice) (archive sound) (uncredited)
John Leguizamo
Rat #2 (voice, uncredited)
