Seth Gamble

Deadpool / Wade Wilson

Jessica Drake

Lady Deadpool / Wanda Wilson

Jennifer White

Comic Domino

Ana Foxxx

Movie Domino

Nikki Delano

Fluffer

Romi Rain

Elektra

Ramon Nomar

The Punisher

Tommy Gunn

Wolverine

Brad Armstrong

Cable

James Bartholet

James LeBlow, Casting Director

Will Ryder

Himself

Axel Braun

Himself

Peter O'Tool

Weasel

Aiden Ashley

Bar Patron (uncredited)

Fliktor

Camera Operator (uncredited)

Hank Hoffman

Crew Member (uncredited)

Avi Love

Mrs. Valerie Hyde (uncredited)

Angela White

Crew Member (uncredited)

Lucky Starr

Woman at the Bar (uncredited)

Danny Wylde

Grip (uncredited)