Akio Otsuka
Solid Snake / Solidus Snake (voice)
田中英行
Hal 'Otacon' Emmerich (voice)
青野武
Roy Campbell (voice)
沢木郁也
Ocelot (voice)
Takumi Yamazaki
Cyborg Ninja (voice)
Banjo Ginga
Liquid Snake (voice)
山本麻里安
Emma Emmerich (voice)
井上喜久子
Rosemary (voice)
飯塚昭三
Peter Stillman (voice)
置鮎龍太郎
Vamp (voice)
Kenyu Horiuchi
Raiden (voice)
冬馬由美
Fortune (voice)
塩屋浩三
Fatman (voice)
阪脩
Sergei Gurlukovich (voice)
郷里大輔
Scott Dolph (voice)
寺瀬今日子
Olga Gurlukovich (voice)
堀之紀
The Sorrow (voice)
藤本譲
President Johnson (voice)
井上喜久子
Karen Hojo (voice)
小松里歌
Others (voice)
今村直樹
Others (voice)
平井啓二
Others (voice)
Keisuke Baba
Others (voice)
Takehiko Watanabe
Others (voice)
森岳志
Others (voice)
坂熊孝彦
Others (voice)